### 7. **Corticosteroids (e.g., prednisone, dexamethasone)**

Corticosteroids are anti-inflammatory drugs used to treat conditions like arthritis, asthma, and autoimmune diseases. Long-term use can lead to a reversible form of cognitive impairment known as “steroid dementia.” ([healthline.com][4])

**Symptoms May Include:**

* Memory loss
* Confusion
* Mood swings([banyantreatmentcenter.com][1])

Discontinuing corticosteroid therapy often leads to the resolution of these cognitive issues.

—

### 8. **Mefloquine (Lariam)**

Mefloquine is an antimalarial drug. The U.S. Food and Drug Administration (FDA) has issued a boxed warning regarding the potential for neuropsychiatric side effects, including depression, hallucinations, and seizures, which may persist even after discontinuing the medication. ([en.wikipedia.org][8])

**Precautions:**

Mefloquine is not recommended for individuals with a history of psychiatric disorders or epilepsy. Healthcare providers should carefully consider the risks before prescribing this medication.([en.wikipedia.org][8])

—

### General Recommendations

* **Consult Healthcare Providers:** Before starting or discontinuing any medication, especially for older adults, consult with a healthcare professional to assess risks and benefits.

* **Regular Monitoring:** Individuals on long-term medications should have regular check-ups to monitor for potential cognitive side effects.

* **Lifestyle Modifications:** Incorporate brain-healthy habits such as regular physical activity, a balanced diet, mental stimulation, and adequate sleep to support cognitive function.

—

### Conclusion

While medications are essential for managing various health conditions, it’s crucial to be aware of their potential impact on cognitive health. The drugs listed above have been associated with an increased risk of dementia, particularly with long-term use. By staying informed and working closely with healthcare providers, individuals can make informed decisions about their treatment plans to minimize risks and promote overall well-being.

* [thetimes.co.uk](https://www.thetimes.co.uk/article/antidepressants-may-speed-memory-loss-dementia-patients-gbsfbrkfp?utm_source=chatgpt.com)
* [nypost.com](https://nypost.com/2025/03/06/health/this-common-menopause-drug-can-worsen-alzheimers-in-women/?utm_source=chatgpt.com)
* [thesun.ie](https://www.thesun.ie/health/14777864/antidepressants-accelerates-deadly-dementia/?utm_source=chatgpt.com)

[1]: https://www.banyantreatmentcenter.com/blog/drugs-linked-to-dementia/?utm_source=chatgpt.com “Drugs That Cause Dementia”
[2]: https://www.health.harvard.edu/blog/could-medications-contribute-to-dementia-2018052313872?utm_source=chatgpt.com “Could medications contribute to dementia? – Harvard Health”
[3]: https://www.goodrx.com/conditions/dementia/these-drugs-could-increase-your-risk-of-dementia?utm_source=chatgpt.com “Drugs Linked to Dementia: The Complete Guide – GoodRx”
[4]: https://www.healthline.com/health/dementia/dementia-medications-to-avoid?utm_source=chatgpt.com “5 Medications to Avoid for People with Dementia”
[5]: https://www.thetimes.co.uk/article/antidepressants-may-speed-memory-loss-dementia-patients-gbsfbrkfp?utm_source=chatgpt.com “Antidepressants ‘may speed up memory loss in dementia patients'”
[6]: https://en.wikipedia.org/wiki/Aripiprazole?utm_source=chatgpt.com “Aripiprazole”
[7]: https://en.wikipedia.org/wiki/Haloperidol?utm_source=chatgpt.com “Haloperidol”
[8]: https://en.wikipedia.org/wiki/Mefloquine?utm_source=chatgpt.com “Mefloquine”